| Ercole de’ Roberti | Italy | 1450–1496 | 16 |
| Bartolomeo Cincani | Republic of Venice | 1450–1523 | 14 |
| Master of Sopetrán | — | 1450 | 4 |
| Albert Bouts | Southern Netherlands | 1450–1549 | 19 |
| Pseudo-Bles | — | 1450–1550 | 1 |
| Juan de la Abadia | Spain | 1450–1498 | 1 |
| Giovanni di Pietro | Spain | 1450–1528 | 11 |
| Antonio del Massaro | Status Pontificius | 1450 | 2 |
| Bernardo Zenale | Duchy of Milan | 1450–1526 | 3 |
| Ludovico Brea | France | 1450–1523 | 1 |
| Maître de Coëtivy | France | 1450 | 1 |
| Colijn de Coter | Southern Netherlands | 1450–1530 | 8 |
| Jean Perréal | Kingdom of France | 1450–1530 | 3 |
| Maître au feuillage en broderie | Southern Netherlands | 1450–1600 | 2 |
| Bernardino de Conti | — | 1450–1525 | 5 |
| Maître du retable de saint Barthélemy | — | 1450–1510 | 16 |
| Maître de Saint-Germain-des-Prés | — | 1450 | 2 |
| Giovanni da Oriolo | — | 1450–1474 | 1 |
| Giovan Battista Bertucci il Giovane | — | 1450–1516 | 4 |
| Master of Riglos | Spain | 1450 | 3 |
| Maître de Liesborn | — | 1450–1495 | 12 |
| Bernardino Butinone | — | 1450–1510 | 6 |
| Andrea Busati | Republic of Venice | 1450–1528 | 1 |
| Hans Mair von Landshut | Holy Roman Empire | 1450–1520 | 3 |
| Bernardino Orsi | — | 1450–1532 | 1 |
| Maître du Livre de Raison | Holy Roman Empire | 1450–1500 | 5 |
| Bartholomäus Zeitblom | Holy Roman Empire | 1450–1520 | 1 |
| Maître de la Passion de Darmstadt | Germany | 1450 | 7 |
| Ercole Banci | — | 1450 | 2 |
| Bernardo di Stefano Rosselli | Republic of Florence | 1450–1526 | 4 |
| Master of the Borghese Tondo | — | 1450–1520 | 2 |
| Giovanni da Piamonte | — | 1450–1475 | 1 |
| Guidoccio Cozzarelli | Italy | 1450–1517 | 6 |
| Maître de San Miniato | — | 1450–1490 | 1 |
| Martín de Soria | — | 1450–1487 | 5 |
| Georges Trubert | France | 1450–1508 | 1 |
| Juan de Borgoña | — | 1450–1525 | 1 |
| Maestro di Castelsardo | — | 1450 | 2 |
| Alvise Donati | — | 1450–1534 | 1 |
| Giovanni Canavesio | — | 1450–1500 | 2 |
| Master of the Thenn Portraits | — | 1450–1600 | 1 |
| Nicolò Rondinelli | Italy | 1450–1510 | 4 |
| Maître de la Guilde de Saint-Georges de Malines | Southern Netherlands | 1450–1508 | 1 |
| Biagio Pupini | Status Pontificius | 1450–1575 | 15 |
| Maître de la Sainte Parenté le Jeune | — | 1450–1515 | 1 |
| Maître du Retable des Écossais de Vienne | Germany | 1450–1501 | 1 |
| Master of the Habsburgs | — | 1450–1550 | 2 |
| Maître d'Uttenheim | — | 1450–1490 | 2 |
| Master of Osma | — | 1450 | 1 |
| Maître de la mort d'Absalon | — | 1450 | 1 |
| Domingo Ram | Kingdom of Aragon | 1450–1507 | 9 |
| Belbello da Pavia | — | 1450–1470 | 2 |
| Hugo de Carpi | Italy | 1450–1523 | 5 |
| Shōkei Kenkō | Japan | 1450 | 5 |
| Kantei | Japan | 1450 | 1 |
| Zhu Duan | Ming dynasty | 1450 | 1 |
| Antonio da Brescia | — | 1450 | 2 |
| Antonio Gambello | Italy | 1450–1481 | 2 |
| Antonio Marescotti | — | 1450 | 8 |
| Maître aux banderoles | Kingdom of the Netherlands | 1450 | 3 |