| Ercole Ferrarese | Italy | 1450–1496 | 16 |
| Bartolomeo Montagna | Republic of Venice | 1450–1523 | 14 |
| Maestro de Sopetrán | — | 1450 | 4 |
| Albrecht Bouts | Southern Netherlands | 1450–1549 | 19 |
| Pseudo-Blesius | — | 1450–1550 | 1 |
| Juan de la Abadía | Spain | 1450–1498 | 1 |
| Giovanni di Pietro | Spain | 1450–1528 | 11 |
| Antonio del Massaro | Status Pontificius | 1450 | 2 |
| Bernardino Zenale | Duchy of Milan | 1450–1526 | 3 |
| Ludovico Brea | France | 1450–1523 | 1 |
| Maestro de Coëtivy | France | 1450 | 1 |
| Colijn de Coter | Southern Netherlands | 1450–1530 | 8 |
| Jean Perréal | Kingdom of France | 1450–1530 | 3 |
| Master of the Embroidered Foliage | Southern Netherlands | 1450–1600 | 2 |
| Bernardino de' Conti | — | 1450–1525 | 5 |
| Maestro del Retablo de San Bartolomé | — | 1450–1510 | 16 |
| Maestro de Saint-Germain-des-Prés | — | 1450 | 2 |
| Giovanni da Oriolo | — | 1450–1474 | 1 |
| Giovanni Battista, I Bertucci | — | 1450–1516 | 4 |
| Maestro de Riglos | Spain | 1450 | 3 |
| Master of Liesborn | — | 1450–1495 | 12 |
| Bernardino Butinone | — | 1450–1510 | 6 |
| Andrea Busati | Republic of Venice | 1450–1528 | 1 |
| Mair von Landshut | Holy Roman Empire | 1450–1520 | 3 |
| Bernardino Orsi | — | 1450–1532 | 1 |
| Master of the Housebook | Holy Roman Empire | 1450–1500 | 5 |
| Bartholomäus Zeitblom | Holy Roman Empire | 1450–1520 | 1 |
| Meister der Darmstädter Passion | Germany | 1450 | 7 |
| Ercole Banci | — | 1450 | 2 |
| Bernardo di Stefano Rosselli | Republic of Florence | 1450–1526 | 4 |
| Master of the Borghese Tondo | — | 1450–1520 | 2 |
| Giovanni da Piamonte | — | 1450–1475 | 1 |
| Guidoccio di Giovanni Cozzarelli | Italy | 1450–1517 | 6 |
| Master of San Miniato | — | 1450–1490 | 1 |
| Martín de Soria | — | 1450–1487 | 5 |
| Georges Trubert | France | 1450–1508 | 1 |
| Joan de Burgunya | — | 1450–1525 | 1 |
| Mestre de Castelsardo | — | 1450 | 2 |
| Alvise Donati | — | 1450–1534 | 1 |
| Giovanni Canavesio | — | 1450–1500 | 2 |
| Master of the Thenn Portraits | — | 1450–1600 | 1 |
| Niccolo Rondinelli | Italy | 1450–1510 | 4 |
| Maestro de Georgsgilde in Mecheln | Southern Netherlands | 1450–1508 | 1 |
| Biagio Pupini | Status Pontificius | 1450–1575 | 15 |
| Maestro de la Santa Parentela el Joven | — | 1450–1515 | 1 |
| Maestro del Altar de Schotten | Germany | 1450–1501 | 1 |
| Maestro de los Habsburgo | — | 1450–1550 | 2 |
| Maestro de Uttenheim | — | 1450–1490 | 2 |
| Maestro de Osma | — | 1450 | 1 |
| Meester van de Dood van Absalom | — | 1450 | 1 |
| Domingo Ram | Kingdom of Aragon | 1450–1507 | 9 |
| Belbello da Pavía | — | 1450–1470 | 2 |
| Ugo da Carpi | Italy | 1450–1523 | 5 |
| Shōkei Kenkō | Japan | 1450 | 5 |
| Kantei | Japan | 1450 | 1 |
| Zhu Duan | Ming dynasty | 1450 | 1 |
| Antonio da Brescia | — | 1450 | 2 |
| Antonio Gambello | Italy | 1450–1481 | 2 |
| Antonio Marescotti | — | 1450 | 8 |
| Master of the Banderoles | Kingdom of the Netherlands | 1450 | 3 |